Harry Gladstone Clarke (born June 1, 1881) was a Canadian parliamentarian and insurance agent.
Clarke was an alderman on Toronto City Council for Ward 2, when he was elected to the Canadian House of Commons in the 1935 federal election as the Conservative Member of Parliament for Rosedale. He was defeated in the summer of 1939 in his attempt to win the nomination as a National Conservative candidate in the 1940 federal election by Harry Jackman. After he and his supporters unsuccessfully tried to obtain an "open convention" in Rosedale in early 1940 to recontest the nomination, he retired from politics.